![\"\"](\"https:\/\/apitherapy.co\/wp-content\/uploads\/2020\/03\/Diapositiva1-2.jpg\")
<\/figure>\n\n\n\nProp\u00f3leo<\/h2>\n\n\n\n
El prop\u00f3leo ha sido evaluado sobre algunos tipos de virus mostrando efectos antivirales relevantes: <\/p>\n\n\n\n La miel de abejas posee efectos antivirales:<\/p>\n\n\n\n Se ha evaluado el efecto de la jalea real contra el virus herpes simple. La jalea real inhibe la replicaci\u00f3n viral y reduce la expresi\u00f3n de prote\u00ednas virales (24).<\/p>\n\n\n\n Puede apreciarse que los mecanismos son diversos lo cual abre la posibilidad de emplear los productos de la colmena en una gran cantidad de infecciones virales. La experiencia cl\u00ednica ha mostrado que en la mayor\u00eda de las infecciones virales se logra la reducci\u00f3n de la carga viral, la intensidad sintom\u00e1tica, calidad de vida y facilita su curaci\u00f3n. <\/p>\n\n\n\n 1. Koonin E V., Senkevich TG, Dolja V V.\nThe ancient virus world and evolution of cells. Biol Direct. 2006; <\/p>\n\n\n\n 2. Katsura Y, Asai S. Evolutionary\nMedicine of Retroviruses in the Human Genome. Am J Med Sci [Internet]. 2019\nDec;358(6):384\u20138. Available from:\nhttps:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002962919303453<\/p>\n\n\n\n 3. Carrasco-Hernandez R, J\u00e1come R, L\u00f3pez\nVidal Y, Ponce de Le\u00f3n S. Are RNA Viruses Candidate Agents for the Next Global\nPandemic? A Review. ILAR J [Internet]. 2017 Dec 15;58(3):343\u201358. Available\nfrom: https:\/\/academic.oup.com\/ilarjournal\/article\/58\/3\/343\/4107390<\/p>\n\n\n\n 4. Wehbe R, Frangieh J, Rima M, El Obeid D,\nSabatier J-M, Fajloun Z. Bee Venom: Overview of Main Compounds and\nBioactivities for Therapeutic Interests. Molecules [Internet]. 2019 Aug\n19;24(16):2997. Available from: https:\/\/www.mdpi.com\/1420-3049\/24\/16\/2997<\/p>\n\n\n\n 5. Albiol Matanic VC, Castilla V. Antiviral\nactivity of antimicrobial cationic peptides against Junin virus and herpes\nsimplex virus. Int J Antimicrob Agents [Internet]. 2004 Apr;23(4):382\u20139.\nAvailable from: https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0924857903004151<\/p>\n\n\n\n 6. Baghian A, Kousoulas KG. Role of the\nNa+,K+ Pump in Herpes Simplex Type 1-Induced Cell Fusion: Melittin Causes\nSpecific Reversion of Syncytial Mutants with the Syn1 Mutation to Syn+\n(Wild-Type) Phenotype. Virology [Internet]. 1993 Oct;196(2):548\u201356. Available\nfrom: https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0042682283715102<\/p>\n\n\n\n 7. Yasin B, Pang M, Turner JS, Cho Y, Dinh\nN-N, Waring AJ, et al. Evaluation of the Inactivation of Infectious Herpes\nSimplex Virus by Host-Defense Peptides. Eur J Clin Microbiol Infect Dis\n[Internet]. 2000 Apr 3;19(3):187\u201394. Available from:\nhttp:\/\/link.springer.com\/10.1007\/s100960050457<\/p>\n\n\n\n 8. Uddin MB, Lee B-H, Nikapitiya C, Kim\nJ-H, Kim T-H, Lee H-C, et al. Inhibitory effects of bee venom and its\ncomponents against viruses in vitro and in vivo. J Microbiol [Internet]. 2016\nDec 26;54(12):853\u201366. Available from:\nhttp:\/\/link.springer.com\/10.1007\/s12275-016-6376-1<\/p>\n\n\n\n 9. Esser AF, Bartholomew RM, Jensen FC,\nMuller-Eberhard HJ. Disassembly of viral membranes by complement independent of\nchannel formation. Proc Natl Acad Sci [Internet]. 1979 Nov 1;76(11):5843\u20137.\nAvailable from: http:\/\/www.pnas.org\/cgi\/doi\/10.1073\/pnas.76.11.5843<\/p>\n\n\n\n 10. Boone LR, Skalka A. Two species of\nfull-length cDNA are synthesized in high yield by melittin-treated avian\nretrovirus particles. Proc Natl Acad Sci [Internet]. 1980 Feb 1;77(2):847\u201351.\nAvailable from: http:\/\/www.pnas.org\/cgi\/doi\/10.1073\/pnas.77.2.847<\/p>\n\n\n\n 11. Brack-Werner R, Erfle V, von Pechmann N,\nNeumann M, Winder D, Kleinschmidt A, et al. Antimicrobial peptides melittin and\ncecropin inhibit replication of human immunodeficiency virus 1 by suppressing\nviral gene expression. J Gen Virol [Internet]. 1998 Apr 1;79(4):731\u201340.\nAvailable from:\nhttps:\/\/www.microbiologyresearch.org\/content\/journal\/jgv\/10.1099\/0022-1317-79-4-731<\/p>\n\n\n\n 12. Hood JL, Jallouk AP, Campbell N, Ratner\nL, Wickline SA. Cytolytic nanoparticles attenuate HIV-1 infectivity. Antivir\nTher [Internet]. 2012;18(1):95\u2013103. Available from:\nhttp:\/\/www.intmedpress.com\/journals\/avt\/abstract.cfm?id=2346&pid=48<\/p>\n\n\n\n 13. Uzair B, Bushra R, Khan BA, Zareen S,\nFasim F. Potential Uses of Venom Proteins in Treatment of HIV. Protein Pept\nLett [Internet]. 2018 Sep 6;25(7):619\u201325. Available from:\nhttp:\/\/www.eurekaselect.com\/163312\/article<\/p>\n\n\n\n 14. Labsk\u00e1 K, Plodkov\u00e1 H, Pumannov\u00e1 M, Sensch\nKH. Antiviral activity of propolis special extract GH 2002 against Varicella\nzoster virus in vitro. Pharmazie [Internet]. 2018;73(12):733\u20136. Available from:\nhttp:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30522559<\/p>\n\n\n\n 15. Alt\u0131ndi\u015f M, Aslan FG, Uzuner H, \u00dcnal H, K\u00f6ro\u011flu\nM, Kula\u00e7 S, et al. [Comparison of Antiviral Effect of Olive Leaf Extract and\nPropolis with Acyclovir on Herpes Simplex Virus Type 1]. Mikrobiyol Bul\n[Internet]. 2020 Jan;54(1):79\u201394. Available from:\nhttp:\/\/www.ncbi.nlm.nih.gov\/pubmed\/32050880<\/p>\n\n\n\n 16. Takeshita T, Watanabe W, Toyama S,\nHayashi Y, Honda S, Sakamoto S, et al. Effect of Brazilian Propolis on\nExacerbation of Respiratory Syncytial Virus Infection in Mice Exposed to\nTetrabromobisphenol A, a Brominated Flame Retardant. Evidence-Based Complement\nAltern Med [Internet]. 2013;2013:1\u20139. Available from:\nhttp:\/\/www.hindawi.com\/journals\/ecam\/2013\/698206\/<\/p>\n\n\n\n 17. D\u00edaz-Carballo D, K.Ueberla, Kleff V,\nErgun S, Malak S, M.Freistuehler, et al. Antiretroviral activity of two\npolyisoprenylated acylphloroglucinols, 7-epi-nemorosone and plukenetione A,\nisolated from Caribbean propolis. Int J Clin Pharmacol Ther [Internet]. 2010\nOct 1;48(10):670\u20137. Available from:\nhttp:\/\/www.dustri.com\/article_response_page.html?artId=7936&doi=10.5414\/CPP48670&L=0<\/p>\n\n\n\n 18. Chang F-R, Hsieh Y-C, Chang Y-F, Lee K-H,\nWu Y-C, Chang L-K. Inhibition of the Epstein\u2013Barr virus lytic cycle by moronic\nacid. Antiviral Res [Internet]. 2010 Mar;85(3):490\u20135. Available from:\nhttps:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0166354209005415<\/p>\n\n\n\n 19. Shimizu T, Hino A, Tsutsumi A, Park YK, Watanabe\nW, Kurokawa M. Anti-Influenza Virus Activity of Propolis in Vitro and its\nEfficacy against Influenza Infection in Mice. Antivir Chem Chemother\n[Internet]. 2008 Feb;19(1):7\u201313. Available from:\nhttp:\/\/journals.sagepub.com\/doi\/10.1177\/095632020801900102<\/p>\n\n\n\n 20. Gekker G, Hu S, Spivak M, Lokensgard JR,\nPeterson PK. Anti-HIV-1 activity of propolis in CD4+ lymphocyte and microglial\ncell cultures. J Ethnopharmacol [Internet]. 2005 Nov;102(2):158\u201363. Available\nfrom: https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874105003740<\/p>\n\n\n\n 21. Lee J Le, Loe MWC, Lee RCH, Chu JJH.\nAntiviral activity of pinocembrin against Zika virus replication. Antiviral Res\n[Internet]. 2019 Jul;167:13\u201324. Available from:\nhttps:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0166354218306016<\/p>\n\n\n\n 22. Watanabe K, Rahmasari R, Matsunaga A,\nHaruyama T, Kobayashi N. Anti-influenza Viral Effects of Honey In Vitro: Potent\nHigh Activity of Manuka Honey. Arch Med Res [Internet]. 2014 Jul;45(5):359\u201365.\nAvailable from: https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0188440914001106<\/p>\n\n\n\n 23. Shahzad A, Cohrs RJ. In vitro antiviral\nactivity of honey against varicella zoster virus (VZV): A translational\nmedicine study for potential remedy for shingles. Transl Biomed [Internet].\n2012;3(2). Available from: http:\/\/imed.pub\/ojs\/index.php\/iam\/index<\/p>\n\n\n\n 24. Hashemipour MA, Tavakolineghad Z,\nArabzadeh SAM, Iranmanesh Z, Nassab SAHG. Antiviral Activities of Honey, Royal\nJelly, and Acyclovir Against HSV-1. Wounds \na Compend Clin Res Pract [Internet]. 2014 Feb;26(2):47\u201354. Available\nfrom: http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25860226<\/p>\n","protected":false},"excerpt":{"rendered":" Desde su descubrimiento los virus han sido objeto de controversia. Incluso su origen no es claro y se debate entre tres teor\u00edas: reliquias de la vida pre-celular, \u201cpar\u00e1sitos\u201d intracelulares o genes que escaparon de c\u00e9lulas y se unieron con unidades funcionales (1). Si bien los virus han sido conocidos por su capacidad para generar enfermedades […]\n","protected":false},"author":1,"featured_media":731,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"spay_email":"","footnotes":""},"categories":[127],"tags":[181,128,245,243,247,246,244,242],"class_list":["post-730","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-apiterapia-basada-en-la-evidencia","tag-apiterapia","tag-apiterapia-basada-en-la-evidencia","tag-apitoxina","tag-jalea-real","tag-miel-de-abejas","tag-propoleo","tag-veneno-de-abejas","tag-virus"],"jetpack_featured_media_url":"https:\/\/apitherapy.co\/wp-content\/uploads\/2020\/03\/antiviral-principal.jpg","_links":{"self":[{"href":"https:\/\/apitherapy.co\/index.php?rest_route=\/wp\/v2\/posts\/730","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/apitherapy.co\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/apitherapy.co\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/apitherapy.co\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/apitherapy.co\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=730"}],"version-history":[{"count":0,"href":"https:\/\/apitherapy.co\/index.php?rest_route=\/wp\/v2\/posts\/730\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/apitherapy.co\/index.php?rest_route=\/wp\/v2\/media\/731"}],"wp:attachment":[{"href":"https:\/\/apitherapy.co\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=730"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/apitherapy.co\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=730"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/apitherapy.co\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=730"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}![\"\"](\"https:\/\/apitherapy.co\/wp-content\/uploads\/2020\/03\/Diapositiva2-2.jpg\")
<\/figure>\n\n\n\nMiel de abejas<\/h2>\n\n\n\n
![\"\"](\"https:\/\/apitherapy.co\/wp-content\/uploads\/2020\/03\/Diapositiva3-1.jpg\")
<\/figure>\n\n\n\nJalea real<\/h2>\n\n\n\n
Referencias bibliogr\u00e1ficas <\/h4>\n\n\n\n